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filingDate 2020-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112225937-B
titleOfInvention A thermosensitive macroporous biohydrogel and its preparation method and application
abstract The invention discloses a temperature-sensitive macroporous biological hydrogel and a preparation method and application thereof. The invention adopts methylcellulose and collagen to be blended, and after air is introduced, the solution is transformed from a solution at a temperature close to body temperature. for hydrogel. No chemical reagents such as porogens and foaming agents are added in the preparation process of the present invention, and the raw materials used are safe and non-toxic. Therefore, the temperature-sensitive macroporous hydrogel of the present invention not only has a large pore size structure (up to 200 μm), good It has good body temperature sensitivity and good biological safety, and can be widely used in the preparation of tissue drug delivery, stem cell therapy and injection therapeutic preparations. In addition, the preparation method of the present invention has the advantages of convenient operation and convenient process, and the required equipment and raw materials are simple and inexpensive.
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