http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112213402-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48e1b1f8aae6a1dc50dc9edb345bf433 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-067 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 |
| filingDate | 2019-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4eea8f52834c1329e571a14d75cbe6b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20d60923e7710bc04f1ad67083e0109a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f956b39529115eda333d8f2336f610fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01f39706999506bc52dd8b8115bcf3be |
| publicationDate | 2021-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112213402-A |
| titleOfInvention | (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride and its isomers detection method |
| abstract | The invention discloses a method for detecting (3R,4R)-1-benzyl-N,4-dimethylpiperidine-3-amine dihydrochloride and its enantiomer, which uses chiral derivatization Pre-column derivatization of 1-benzyl-N,4-dimethylpiperidine-3-amine dihydrochloride by reagent isothiocyanate or isocyanate, and detection by high performance liquid chromatography. The present invention realizes (3R,4R)-1-benzyl-N,4-dimethylpiperidine-3-amine dihydrochloride and (3S,4S)-1-benzyl-N,4-dimethyl The separation of base piperidine-3-amine dihydrochloride has low detection cost and good sensitivity, specificity and accuracy, and is an effective detection method for the quality control of tofacitinib citrate starting materials. In this way, the product quality of tofacitinib citrate and the patient's medication safety are further guaranteed. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113549075-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113899831-A |
| priorityDate | 2019-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.