http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112210577-A

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filingDate 2020-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9edab8e061d88977064925bab3199754
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publicationDate 2021-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112210577-A
titleOfInvention A kind of method for producing β-thymidine by fermentation
abstract The invention discloses a method for producing β-thymidine by fermentation, which includes preparing bacterial protein, preparing seed medium, preparing fermentation medium, preparing feeding medium and fermenting culture; the bacterial protein used in the medium is Desalting, concentrating, and drying the riboflavin-producing yeast liquid to obtain bacterial protein; in the process of fermenting and producing β-thymidine, the feeding medium is automatically added according to the fermentation time period to adjust the glucose concentration, and the glucose concentration is 10-20g in 0-15 hours /L; 15-30 hours glucose concentration 10-15g/L; 30-60 hours glucose concentration 5-10g/L; stop feeding 2 hours before putting the tank, and control the glucose concentration to be 0g/L put the tank. The method replaces part of the organic nitrogen source with riboflavin cell protein, which can improve the fermentation level of β-thymidine and reduce the production cost; according to the glucose concentration in the fermenter, the feeding medium is automatically added according to the fermentation time period, which greatly reduces the production cost, while saving energy and improving labor productivity.
priorityDate 2020-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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