http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112209986-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J19-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-0005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 |
| filingDate | 2020-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112209986-B |
| titleOfInvention | A kind of steroid compound, preparation method and application |
| abstract | The invention discloses a steroidal compound, a preparation method and application thereof. The preparation method of the steroidal compound comprises: taking the leaf of the open arrow as the extraction raw material, extracting with alcohol to obtain an extract, and then passing the extract through an organic solvent Steroidal compounds were obtained by extraction and column chromatography. Compounds 1-9 are all steroidal components, among which compounds 1 and 4 are cardiac glycosides, compounds 2, 3, 5, 6, and 7 are spirosterane steroidal saponins or saponins, and compounds 8 and 9 are Furostanoid steroidal saponins. Antibacterial activity studies showed that compound 3 had excellent antibacterial activity against Bacillus subtilis (B.subtilis), Staphylococcus aureus (S.aureus), and Candida albicans (C.albicans). The invention preliminarily reveals the material basis of the antibacterial activity of the open arrow, which is of great significance for the further design and development of new antibacterial drugs. |
| priorityDate | 2020-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.