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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0478
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F13-00
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04
filingDate 2020-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112209970-B
titleOfInvention Preparation method and application of technetium-99 m labeled isonitrile-containing glutamic acid-urea derivative
abstract The present invention discloses a kind of 99m Tc‑(CNGU) 6 ] + The complex is prepared by synthesizing the ligand CNGU and the ligand CNGU 99m Tc‑(CNGU) 6 ] + The preparation of the complex comprises two steps to obtain 99m Tc‑(CNGU) 6 ] + And (3) a complex. The complex has the advantages of simple preparation, high radiochemical purity, good stability and better water solubility. The derivative has specific uptake in tumor sites of male nude mice with LNCaP tumor BALB/C, and can be used as a novel tumor radiopharmaceutical targeting PSMA and used for prostate cancer diagnosis.
priorityDate 2020-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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