http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112209859-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-40 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-08 |
filingDate | 2020-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112209859-B |
titleOfInvention | Preparation method of Iguratimod intermediate |
abstract | The invention discloses a preparation method of an Iguratimod intermediate, which comprises the steps of taking formic acid as a starting material, reacting with N, N-Carbonyl Diimidazole (CDI) by an active ester method to obtain formyl imidazole with higher activity, and reacting with 2-amino-1- (2-methoxy-4-methanesulfonamide-5-phenoxyphenyl) ethanone hydrochloride to prepare the important intermediate compound of the Iguratimod. The method has the advantages of safety, environmental protection, simple operation, high yield, good product purity, suitability for industrial production and the like, and is suitable for preparing the Iguratimod intermediate. |
priorityDate | 2020-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.