http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112206359-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-04 |
filingDate | 2020-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112206359-B |
titleOfInvention | Self-mineralized collagen membrane, preparation method and application |
abstract | The invention discloses a self-mineralized collagen membrane, a preparation method and application thereof. The self-mineralized collagen film is prepared by the following method: (1) polyanion polyelectrolyte solution with the concentration of 2-10 mg/mL, and adjusting the pH value of the solution to 6.0; (2) dissolving a chemical cross-linking agent in the solution in the step (1), standing for 1-15 min at normal temperature, and adjusting the pH value to 7.0 to obtain a polyelectrolyte solution to be cross-linked; (3) and (3) placing the GBR collagen membrane in the polyelectrolyte solution to be crosslinked in the step (2), and reacting for 1-15 min at normal temperature to obtain the self-mineralized collagen membrane. The self-mineralized collagen membrane is applied to preparing bone repair materials, osteogenic materials or bone materials. After the self-mineralization film is implanted into a body, calcium and phosphorus ions in body fluid can be spontaneously enriched and the in-fiber mineralization can be gradually induced, so that the in-vivo conversion of the collagen film from a tough material to a rigid material is realized. |
priorityDate | 2020-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.