| abstract |
The invention discloses a hyaluronic acid/epsilon-polylysine antibacterial hydrogel and a preparation method and application thereof 3+ And (4) the solution of (1). Firstly, generating free radicals by using the carbon-carbon double bond of glycidyl methacrylate through ultraviolet irradiation to polymerize; secondly, the polylysine and the hyaluronic acid are used for generating electrostatic attraction and are attached to the surface of the photo-crosslinking hydrogel; finally using Fe 3+ The chelating effect of the compound can increase the crosslinking density to form the antibacterial hydrogel, and the antibacterial hydrogel has the advantages of controllable performance, excellent toughness, good biocompatibility, biodegradability, light forming and the like, has mild and controllable preparation conditions, and can be applied to the field of biomedical materials such as cartilage tissue engineering materials and the like. |