http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112174871-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08 |
| filingDate | 2020-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112174871-B |
| titleOfInvention | Process for preparing indolines |
| abstract | The invention relates to a method for preparing indoline, which is characterized by comprising the following steps: a. performing condensation and ring closure on phenylhydrazine hydrochloride or phenylhydrazine hydrochloride containing substituent groups and methyl ketone compounds in a solvent under the non-catalytic condition to generate C2-methylindole or derivatives thereof, and then cooling, salting out, filtering and desolventizing; b. c, dissolving the salt generated in the step b in water, then performing alkaline hydrolysis in a solvent and an alkali liquor, layering, desolventizing and distilling to obtain a product such as: 1,3, 3-trimethyl-2-methylindoline or a derivative thereof. The whole process is simple, the amount of three wastes is less, the cost is low, the yield is high, and the method is a green process which is suitable for industrial amplification and has outstanding economic benefits. |
| priorityDate | 2020-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.