| abstract |
The present invention provides a water-soluble rhodamine-based fluorescent/colorimetric dual-mode probe and a preparation method and application thereof. The preparation method of the probe of the invention comprises the steps of: reacting rhodamine 6G and hydrazine to prepare rhodamine 6G hydrazide; reacting polyethylene glycol and 4-aldehyde benzoic acid to prepare benzaldehyde-terminated polyethylene Diol; rhodamine 6G hydrazide and benzaldehyde-terminated polyethylene glycol were reacted to prepare a water-soluble rhodamine-based fluorescent/colorimetric dual-mode probe. The dual-mode probe obtained by the invention has good water solubility, biocompatibility and safety, and can be used in the field of biofluorescence imaging or disease diagnosis; for detecting ferric ions, the sample preparation is simple, and can be observed through fluorescence emission and naked eyes. , and showed high selectivity, sensitivity and anti-interference ability, and a wide range of pH. |