http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112156094-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c0aacf4fc329ccaa1dafb12bedf7966 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-183 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2020-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_186655d3c4c6a065abd0edc277034101 |
| publicationDate | 2021-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112156094-A |
| titleOfInvention | A kind of preparation method of camptothecin derivative/oligopeptide@ZIF-8 nanometer drug loading system |
| abstract | The present invention proposes a preparation method of a camptothecin derivative/oligopeptide@ZIF-8 nano-drug-carrying system, which includes the non-covalent bond effect of the camptothecin derivative and the oligopeptide to enhance the dissolution of the camptothecin derivative Then, the camptothecin derivative/oligopeptide@ZIF-8 nano-drug-loading system was prepared by combining camptothecin derivatives/oligopeptides with ZIF-8 organometallic framework nanoparticles. The ZIF-8 backbone can effectively load the non-covalent system of camptothecin derivatives/oligopeptides. The system construction of oligopeptides and camptothecin derivatives enhances the solubility of camptothecin derivatives, which can be applied to the targeting of clinical drugs. treatment, with good prospects for development. |
| priorityDate | 2020-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.