http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112143410-B

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filingDate 2020-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112143410-B
titleOfInvention Injectable biological adhesive and preparation method and application thereof
abstract The invention discloses an injectable biological adhesive, a preparation method and application thereof, and belongs to the technical field of high polymer materials and biological materials. The invention selects the saccharide macromolecules-glucan and chitosan oligosaccharide with good biocompatibility as the matrix, mixes the matrix with dopamine and an oxidation crosslinking agent, disperses the matrix in an aqueous solution, and carries out rapid gelation to obtain the multi-crosslinking biological adhesive. The biological adhesive material obtained by the invention has the advantages of injectability, convenient practical application and operation, application to skin tissues, capability of injecting required amount according to the required adhesive size and the like, has higher mechanical strength, no cytotoxicity and excellent tissue adhesive performance, can be applied to the adhesion of various materials such as animal body epidermis, internal body tissues and organs, glass, metal and oxides thereof, sealant, plastics and the like in clinical operation, and has wide application prospect in the fields of tissue adhesion and repair, hemostasis, packaging, sealing and the like in clinical medicine.
priorityDate 2020-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 45.