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publicationDate 2020-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112121181-A
titleOfInvention A method for evaluating the efficacy of health care products to enhance immunity
abstract The invention belongs to the technical field of detection. The invention discloses a method for evaluating the immunity-enhancing efficacy of health care products, which comprises using zebrafish to set up a model control group and a test product group, taking fluorescence pictures, analyzing the fluorescence intensity S of macrophages in the tail of the zebrafish, and using the fluorescence intensity S to calculate Enhance immunity. The method does not need to explore the concentration of the reagents, and the reagents used are relatively stable, which can reduce the experimental steps; the experimental period of the zebrafish enhanced immunity model is shorter than that of the mouse experiment, only 24 hours; because the zebrafish has low feeding cost and small volume , The characteristics of short development cycle and high number of single eggs can be evaluated for multiple samples at the same time; the sum of fluorescence intensity S of macrophages in the tail of zebrafish is used as the judgment standard, as long as the zebrafish in the test group is higher than the model control group. The significant difference can be judged to have the effect of enhancing immunity; the used inducer vinorelbine is a common chemotherapeutic drug with less toxic effect.
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