http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112121029-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-643 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 |
| filingDate | 2020-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112121029-B |
| titleOfInvention | Bionic dopamine polymerization drug-loaded nano delivery system and preparation method thereof |
| abstract | The invention belongs to the field of pharmacy, and discloses a bionic dopamine polymerization drug-loaded nano-delivery system which comprises dopamine polymerization drug-loaded nanoparticles prepared from dopamine and anti-tumor drugs, and bionic tumor targeted protein or polypeptide grafted on the surface of polydopamine. The dopamine is coated in the polydopamine in a polymerization drug loading manner, so that the encapsulation rate of the dopamine is obviously improved, and the dopamine has higher drug loading capacity; and then, the bionic tumor targeting protein or polypeptide is covalently grafted to the surface of the polydopamine, so that the nano delivery system is endowed with bionic characteristics and targeting functions. The nano delivery system prepared by the invention has the characteristics of pH, ROS and photo-thermal triple response rapid drug release, can realize the purpose of tumor chemotherapy-photo-thermal combined treatment through tumor targeting, and has good application prospect in the aspect of tumor targeted combined treatment. |
| priorityDate | 2020-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 96.