http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112113942-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_819d2d00412d671253120d16a2f09908 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6402 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| filingDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5964ecac08d6d1b4b2eea2d15d4a8f8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a4cf522a549258d1880768ed6afa02b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02e7a5aa280289c48b6f5e70ab69bd08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d2e997b539a7ca603497b8153f7eec5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4743e4a734df7bbd1e903c35dd772733 |
| publicationDate | 2020-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112113942-A |
| titleOfInvention | An Affinity Analysis Technique Based on Molecular Chemical Trend Shift |
| abstract | The invention discloses an affinity analysis technology based on molecular chemical directional displacement. By constructing a chemical gradient field between microfluids with low Reynolds number, the spontaneous directional migration distance of receptor molecules to ligands is observed; The displacement is correlated with the association reaction information such as ligand concentration and coordination number, and the dissociation constant of the intermolecular interaction is extracted. Different from the binding force measurement in the traditional homogeneous system, the flowing heterogeneous diffusion system can more accurately describe the transient space-time of microscopic molecular reactions, and is closer to the ideal ensemble model of statistical thermodynamics, so it is more indicative. The invention is suitable for the combined analysis of multiple receptor/ligand pairs, and can reveal the stability constants at all levels and the quantitative relationship between them and reaction metrology more comprehensively, comprehensively and efficiently through the quantized chemotaxis step phenomenon. |
| priorityDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 277.