http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112094240-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-96 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 |
| filingDate | 2020-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112094240-B |
| titleOfInvention | Method for synthesizing quinazoline-2, 4(1H,3H) -diketone compound |
| abstract | The invention discloses a method for synthesizing quinazoline-2,4(1 H ,3 H ) A method for preparing diketone compounds, belonging to the technical field of synthesis of nitrogen heterocyclic compounds. The technical scheme provided by the invention has the key points that: the method comprises the steps of taking an anthranilic acid compound and an amine compound as reaction raw materials, CO as a carbonylation reagent, Pd (II) as a catalyst, KI or KI/AcOH as an additive, and Cu (OAc) 2 、O 2 Or Cu (OAc) 2 /O 2 Is used as an oxidant, and the target product quinazoline-2, 4 (1) is prepared by one-pot multi-component reaction in acetonitrile solvent H ,3 H ) -diketones. The method has the advantages of simple and easily obtained raw materials, short synthetic route, high atom economy, high step economy, mild reaction conditions, various product structures, high yield of most target products and the like. |
| priorityDate | 2020-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.