http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112089843-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-724 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-724 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate | 2020-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112089843-B |
| titleOfInvention | Combination drug for anti-heart failure and its application in the preparation of anti-heart failure drug |
| abstract | The invention discloses an anti-heart failure combined drug and the application of a steroid aldosterone receptor antagonist and β-cyclodextrin combined in the preparation of an anti-heart failure drug. The combined drug contains dilute agent, binder, disintegrant, antioxidant, emulsifier, solubilizer, steroid aldosterone receptor antagonist and β-cyclodextrin, the combined drug for anti-heart failure according to the embodiment of the present invention is relatively Compared with the single use of spironolactone, β-cyclodextrin, nebivolol, and amlodipine, the combination of steroidal aldosterone receptor antagonists and β-cyclodextrin can significantly increase cell survival, and can reduce the The content of ROS in cells treated with doxorubicin can significantly improve the antioxidant capacity of cells, which in turn can greatly improve the anti-heart failure effect of the drug. |
| priorityDate | 2020-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 245.