http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112079895-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 |
| filingDate | 2020-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112079895-B |
| titleOfInvention | Preparation method and application of triterpenoid with liver protection activity in ganoderma lucidum |
| abstract | The invention discloses a preparation method and application of two triterpene compounds with liver protection activity in medicinal fungus ganoderma lucidum, wherein the structural formulas of the two triterpene compounds, namely a compound I and a compound II are respectively shown as I and II: the preparation method of the two triterpene compounds comprises the steps of taking fruiting bodies of ganoderma lucidum as a raw material, extracting and extracting the fruiting bodies by using a chemical solvent, carrying out primary separation by using normal phase column chromatography, carrying out MCI (methanol-methane-acid) chromatography decoloration, carrying out normal phase column chromatography separation, and carrying out semi-preparative HPLC (high performance liquid chromatography) separation to obtain the triterpene compounds. The application refers to the application of the two triterpene compounds in preparing liver protection medicines. The invention separates triterpene methyl ganoderic acid C and 3 beta, 7 beta-dihydroxy-11, 15, 23-tricarbonyl-lanostane-8, 16-diene-26-carboxylic acid from ganoderma lucidum for the first time, and the preparation method is simple and has high purification degree; in addition, the invention discovers that the triterpenoid has better liver protection activity for the first time, and provides a basis and a new idea for the extraction of the triterpenoid and the medicinal research. |
| priorityDate | 2020-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.