| abstract |
The invention relates to a medical metal surface long-acting anti-infection and highly effective functional coating which can generate osseointegration and a preparation method thereof, in the invention, multifunctional physiologically necessary metal ions, inorganic acid radical ions and the like and medical metal surface nano-fibers, nano-pore wall inorganic salts generate ion exchange and modification, and then are put into bionic physiological liquid for mineralization reaction, calcium phosphate coatings which are similar to bone mineral chemical compositions and have different particle size gradient distributions are deposited in nano-pores, nano-fiber gaps and the upper surface of a fiber layer, the mineralization coatings effectively regulate long-acting release of the deposited functional ions on the nano-fibers and enhance the integration efficiency and the bonding strength with bones, thereby obtaining the performances of long-acting anti-infection and firm osseointegration; the invention has simple and economic preparation process, stable function and outstanding effect of the coating, and can be suitable for surface modification of medical metal and alloy endophytes which need to be permanently integrated with bones, such as orthopedics implanted prostheses, oral implants and the like. |