| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4706
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-13 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4706
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate |
2019-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2022-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-112076320-B |
| titleOfInvention |
A kind of composition with antitumor effect and application thereof |
| abstract |
The present invention provides a composition with anti-tumor effect and application thereof. The composition with anti-tumor effect comprises at least one of a mitophagy inhibitor, a lysosome inhibitor, and metformin. The addition of metformin can inhibit tumor growth by inhibiting mitochondrial respiration, while enhancing the ability of intracellular mitophagy; adding a mitophagy inhibitor or lysosomal inhibitor to block mitophagy can significantly promote metformin-induced tumor cell death. |
| priorityDate |
2019-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |