| abstract |
The invention belongs to the technical field of medicine, and relates to phosphoramidate derivatives of nucleoside compounds and uses thereof, as well as pharmaceutical compositions containing such compounds, which can be used as antiviral reagents, especially anti-novel coronavirus (SARS-CoV-2 ) reagent. The present invention also relates to methods of preparing such compounds and pharmaceutical compositions, and their use in the prevention or treatment of viral infections, including but not limited to, Flaviviridae, Filoviridae, Enteroviridae, Use in Myxoviridae, Paramyxoviridae, Coronaviridae, especially novel coronavirus (SARS‑CoV‑2) infections. |