http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112062760-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 |
| filingDate | 2020-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112062760-B |
| titleOfInvention | NO donor type quinoline derivative and preparation method and application thereof |
| abstract | The invention belongs to the field of biological medicines and discloses an NO donor type quinoline derivative shown as a formula I, wherein R is 1 、R 2 Each independently selected from H, F, 3,4, 5-trialkoxyphenyl and 3,4, 5-trialkoxyphenylamino, and n is a positive integer of 1-5; the alkoxy is C1-C3 alkoxy. The preparation method of the compound has mild reaction conditions, low toxicity of used reagents, easily obtained raw materials, convenient post-treatment and higher yield. The invention also discloses application of the NO donor type quinoline derivative in preparing antitumor drugs, wherein the NO donor type quinoline derivative has excellent antitumor activity which is improved or equivalent to that of a quinoline parent nucleus. |
| priorityDate | 2020-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 97.