http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112062742-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-10 |
filingDate | 2020-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112062742-B |
titleOfInvention | Preparation method of tylosin |
abstract | The invention belongs to the technical field of medicines, and particularly relates to a preparation method of tylosin. The tylosin of the invention is prepared by reacting a compound N-9, N-butyllithium and a compound N-8 to obtain a compound N-10-a, then adding triethylsilane and boron trifluoride diethyl etherate to react to obtain a compound N-11, and then adding Lewis acid to react. The preparation method shortens the synthetic route of the tylosin, and the obtained tylosin has high yield, low impurity content and stable property. |
priorityDate | 2020-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 137.