http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112053414-A

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filingDate 2020-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10a79d241f6aa2e3fde850f3b553bdd6
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publicationDate 2020-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112053414-A
titleOfInvention A method for rapid extraction of pharmacokinetic parameters from dynamic contrast-enhanced magnetic resonance imaging data
abstract The invention discloses a method for rapidly extracting pharmacokinetic parameters from dynamic contrast-enhanced magnetic resonance imaging data: collecting quantitative T1 imaging data, and using DCE - MRI sequence to collect subject's DCE-MRI data as an experiment DCE‑MRI data; and calculate the intravascular contrast agent concentration change curve C p (t) according to the experimental DCE‑MRI data, and use the least squares method to fit the eTofts model to obtain the pharmacokinetic parameters; According to C p (t) Perform data enhancement: use the random linear combination method to obtain simulated angiographic contrast agent concentration data, and obtain simulated DCE-MRI data through the eTofts model; build a dual-stream convolutional neural network Dual-CNN model, and initialize model parameters; dual-stream volume Integrative neural network model training; use the trained Dual‑CNN model to extract pharmacokinetic parameters. The method provided by the present invention can significantly improve the speed of extracting pharmacokinetic parameters from DCE-MRI data, and accelerate the speed of reconstructing tissue physiological parameter maps.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112213346-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114088901-A
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priorityDate 2020-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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