http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112047962-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 2020-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112047962-B |
| titleOfInvention | 2H-thiazolo [3,2-b ] -1,2, 4-triazine-3, 7-diketone derivative and application thereof |
| abstract | The invention discloses 2H-thiazolo [3,2-b ] of a general formula I]-1,2, 4-triazine-3, 7-dione derivatives or pharmaceutically acceptable hydrates, salts thereof, including stereoisomers or tautomers thereof, R in formula I 1 And R 2 Optionally 1,2 or 3 independently selected from hydrogen, alkyl, alkoxy, halogen, hydroxy, acetyl, propionyl, nitro or trifluoromethyl. 2H-thiazolo [3,2-b ]]The (E) -1,2, 4-triazine-3, 7-diketone derivatives have obvious inhibitory effect on acetylcholinesterase and are used for enhancing the memory of patients suffering from dementia and Alzheimer's disease. The invention also relates to a preparation method of the compound and application of the compound in preparing a medicament for treating senile dementia. |
| priorityDate | 2020-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 142.