http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112047856-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12 |
| filingDate | 2019-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2023-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2023-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112047856-B |
| titleOfInvention | Chiral α-amidoaldehyde and its preparation method |
| abstract | The present invention relates to a chiral α-amido aldehyde and a preparation method thereof, the method comprising the following steps: the α-dehydroamido aldehyde represented by the following general formula (1) is catalyzed by a bisphosphine-rhodium complex , reduction reaction with hydrogen in an organic solvent to obtain the chiral α-amidoaldehyde compound represented by the following general formula (2). This synthesis route adopts the method of asymmetric catalytic hydrogenation, the process is simple, efficient and green, and is very suitable for industrial mass production. The product chiral amido aldehyde can be further derivatized into chiral ligands and chiral drug intermediates. |
| priorityDate | 2019-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.