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filingDate 2020-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112007209-B
titleOfInvention CS/QCS/zwitterion/epoxidized zwitterion antibacterial and release integrated gel dressing and preparation method thereof
abstract The invention discloses a CS/QCS/zwitterion/epoxidized zwitterion sterilization-resistant and release integrated gel dressing and a preparation method thereof, wherein the dressing has the functions of dual bacterium adhesion resistance, dual contact sterilization, and salt response release of dead bacteria, so that the formation of a bacterial biofilm is effectively resisted; firstly, preparing quaternized chitosan with a certain grafting degree through an epoxy ring-opening reaction, and preparing epoxidized zwitterions with a certain copolymerization ratio through a free radical copolymerization reaction; dissolving Chitosan (CS) in a water phase, sequentially adding quaternized chitosan, zwitterions, AAm, MBAA and APS, pouring after centrifugal defoaming, and carrying out one-pot reaction to obtain gel; finally, the gel is soaked in an epoxidized zwitter-ion solution, TEA is added, and the gel is reacted in an oven for a period of time to obtain the sterilization and release resistant integrated gel dressing which has the advantages of dual bacterial adhesion resistance, dual contact sterilization and salt response dead bacteria release, and is expected to be used for treating wound infection.
priorityDate 2020-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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