http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112006983-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0057 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 |
| filingDate | 2020-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112006983-B |
| titleOfInvention | Nano self-assembly and preparation method and application thereof |
| abstract | The invention discloses a nanometer self-assembly body and a preparation method and application thereof, the preparation method comprises the steps of carrying out chemical coupling on insulin-like growth factor 1(IGF1) and an amphiphilic polymer to prepare the amphiphilic polymer (ABC-IGF 1 for short) which actively targets liver cancer cells, then mixing an organic Dye (Dye) with ABC-IGF1, and forming the light-responsive nanometer self-assembly body (Dye-ABC-IGF1) which actively targets the liver cancer cells by a self-assembly technology, so that the stability and the optical activity of the organic Dye can be effectively improved, the capability of actively targeting the liver cancer cells is also endowed, and the nanometer self-assembly body can be used for real-time fluorescence imaging of the liver cancer cells, in vivo and in vitro; can generate a large amount of singlet oxygen under the irradiation of laser to effectively inhibit the proliferation of liver cancer cells, and is further applied to the treatment of liver cancer. |
| priorityDate | 2020-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.