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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-88
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filingDate 2017-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111999424-B
titleOfInvention Subclinical pelvic inflammatory disease markers and their use
abstract The invention belongs to the field of biotechnology, and relates to a series of metabolites used in the diagnosis of subclinical pelvic inflammatory disease. The present invention systematically screens metabolites in blood through a metabolomics method based on liquid chromatography-mass spectrometry, and finds metabolites that are significantly correlated with the occurrence of subclinical pelvic inflammatory disease as biomarkers of the disease. The metabolites include: lysophosphatidic acid 16:0/0:0, 1-phosphoceramide d18:1/16:0, stearamide, linoleic acid, stearic acid, phosphatidylethanolamine P-18: 0/0:0, Phosphatidylethanolamine P‑18:0/0:0, Lysophosphatidylethanolamine P‑20:0/0:0, Indole Sulfate, 3‑Indolepropionic Acid, p‑Cresol . The biomarkers found in the present invention can be used for the non-invasive diagnosis and indicated treatment of subclinical pelvic inflammatory disease, and have obvious advantages compared with the clinical method that requires surgery for diagnosis.
priorityDate 2017-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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