http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111991364-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-32 |
| filingDate | 2020-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111991364-B |
| titleOfInvention | A kind of lomerizine hydrochloride osmotic pump tablet and preparation method thereof |
| abstract | The invention relates to the technical field of pharmaceutical engineering, and specifically discloses a lomerizine hydrochloride osmotic pump tablet, comprising a tablet core and a coating layer wrapped on the outside of the tablet core; the tablet core includes a drug layer and a booster layer , the coating layer is obtained by coating the tablet core with the coating liquid; in parts by weight, the drug layer includes 1 part of lomerizine hydrochloride solid dispersion and 8-10 parts of filler; In parts by weight, the booster layer includes 5-7 parts of osmotic pressure enhancer, 1-3 parts of swelling material and 0.05-0.2 parts of lubricant; in parts by weight, the coating liquid includes 30 parts of semi-permeable membrane material , 3-6 parts of permeability regulator, 3-15 parts of plasticizer, 3-15 parts of porogen and 800-1000 parts of solvent; the invention also discloses a preparation method of the lomerizine hydrochloride osmotic pump tablet; The invention combines the solid dispersion solubilization technology with the osmotic pump tablet controlled release technology, which can not only significantly prolong the drug constant-speed release time, but also improve the solubility and absorption properties of the active drug components. |
| priorityDate | 2020-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.