| abstract |
It relates to a macrocyclic compound as a CDK inhibitor, its preparation method and its application in medicine. Specifically, it relates to a novel macrocyclic compound represented by general formula (I), its preparation method and pharmaceutical composition containing the compound, and its use as a therapeutic agent, especially as a CDK inhibitor and its use in the treatment of Use of cancer, inflammation, viral infection, cardiac hypertrophy or HIV, wherein each substituent of general formula (I) is as defined in the specification. |