| abstract |
The present invention discloses important antigenic epitopes SEQ ID: 01 and SEQ ID: 02 for COVID-19 antibody detection, and recombinant proteins containing the antigenic epitopes can be used for the preparation of anti-COVID-19 antibodies such as IgM and IgG. Anti-COVID-19 antibody detection reagents are an effective supplement to 2019-nCoV nucleic acid detection, and can be used to screen contacts of 2019-nCoV, as well as people who have acquired immunity. The invention overcomes the problems of insufficient single S protein antigenic epitope, insufficient detection sensitivity of anti-COVID-19 IgM antibody, etc. The anti-new crown antibody detection reagent prepared by using the recombinant protein containing the new epitope of SEQ01-04 has high sensitivity, stable performance, Qualitative accuracy and other advantages. |