| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5805227aef9b285998ba484773644708 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-54 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 |
| filingDate |
2019-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4eb2e3ce0d1034f952cd8e1dbe5af79b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c12d0ddd014f124b01fd92029466402
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6b80edbd6288dd60da6c0391e8097b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfa2ca8f6fa9f37b7f03fd26da929322
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85dfb6520d2d356e9812ce5973c9cc23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f219d5041f08773a11c8b09d90b5de7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12e070ad63739d8ba8050f5002b7fb72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d659fddce6717afcfe4f3abab3f353c5 |
| publicationDate |
2020-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-111978332-A |
| titleOfInvention |
Maytansine dechloride, midbody, preparation method and application thereof |
| abstract |
The invention discloses a maytansine dechloride shown as a formula I, an intermediate, and a preparation method and application thereof. The invention provides a maytansine dechloride as shown in a formula I; the method can be used as an impurity standard substance for researching impurities of maytansine DM1, establishing an analytical method for the quality control of maytansine DM1, and selecting a proper method to effectively remove the impurities; is helpful for improving the quality of maytansine DM1 and even ADC medicaments and the safety and the effectiveness of clinical application. The invention also provides a preparation method of the maytansine dechloride shown as the formula I and an intermediate thereof. |
| priorityDate |
2019-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |