| abstract |
The invention provides a method for screening the extraction process of total astragalus saponins based on a zebrafish vascular injury model and an application thereof, belonging to the technical field of detection of active components of traditional Chinese medicines. The invention simulates the myocardial cell damage or necrosis symptoms of patients by applying zebrafish intersegmental vascular injury, investigates the effect of total astragalus saponins on zebrafish angiogenesis, and determines its angiogenesis rate, thereby establishing a sensitive, feasible and repeatable The test method of total astragalus saponins promoting zebrafish ISV generation, and the optimal extraction process of astragalus total saponins to promote the relative growth rate of zebrafish intersegmental blood vessels, so it has good practical application value. |