http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111956868-A

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filingDate 2020-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e779f3b146c7a4c5c4d13adb9b4912f7
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publicationDate 2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111956868-A
titleOfInvention A kind of small-caliber composite multilayer artificial blood vessel and preparation method thereof
abstract The invention discloses a small-caliber composite multi-layer artificial blood vessel and a preparation method thereof. The present invention prepares a chitosan/gelatin composite gel coating by preparing a chitosan/gelatin mixed solution as an electrolyte and depositing a chitosan/gelatin composite gel on the surface of a needle electrode by using electrophoretic deposition technology; Using the composite gel coating as a base, the outer layer of sodium alginate/chitosan is constructed on its surface by layer-by-layer self-assembly to form a composite multi-layer gel of chitosan/gelatin/sodium alginate; After the multi-layer gel, the chitosan/gelatin/sodium alginate composite multi-layer artificial blood vessel can be obtained by freeze-drying the special multi-layer structure of natural blood vessels. Through the above method, the present invention can quickly and conveniently prepare an artificial blood vessel with a small diameter and good mechanical properties; and the overall preparation process is easy to control, and the prepared composite multi-layer artificial blood vessel has good biocompatibility and high safety in use, and can meet practical requirements. application needs.
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priorityDate 2020-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 40.