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filingDate 2020-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111956863-B
titleOfInvention Anion-cation co-doped nano calcium phosphate antibacterial material and preparation method thereof
abstract The invention discloses an anion and cation co-doped nano calcium phosphate antibacterial material and a preparation method thereof. Anion fluorine, gamma-PGA, cation copper, zinc, magnesium or silver ions are doped into the calcium phosphate crystal structure to form the anion and cation co-doped nano calcium phosphate antibacterial material. The invention adds a small amount of Cr into the gamma-PGA solution by circularly adjusting the pH value 3+ Preparing gamma-PGA modifier, and adding Ca to the gamma-PGA and calcium phosphate crystal 2+ And the combination effect is also generated, so that the preparation of the fluoride ions, the gamma-polyglutamic acid and the metal ion anion-cation co-doped nano calcium phosphate is achieved, the antibacterial property is good, the degradation rate of the metal ions and the fluoride ions can be regulated, and the biological properties of resisting infection, promoting angiogenesis, promoting bone formation and the like are improved.
priorityDate 2020-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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