| abstract |
The invention provides a combined drug method for treating tumors and its application. The combined drug method combines chimeric antigen receptor immune cell therapy with chemotherapy, and has stronger anti-tumor effect than single chemotherapy or single immune cell therapy. tumor effect. At the same time, the dosage of chemotherapeutic drugs can be reduced, and the toxic and side effects produced by the chemotherapeutic drugs can be reduced. Overcome the problems of off-target caused by the high heterogeneity of the tumor and the unsatisfactory therapeutic effect caused by the singularity of the target in the process of CAR-T cell treatment of tumors. |