http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111944819-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57449 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate | 2020-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111944819-B |
titleOfInvention | Ovarian cancer aptamer capable of being rapidly screened and application of ovarian cancer aptamer in preparation of ovarian cancer detection preparation |
abstract | The invention discloses a nucleic acid aptamer capable of being used for detecting early ovarian cancer tissues and application of the nucleic acid aptamer in early clinical detection of ovarian cancer. The sequence of the aptamer is selected from any one of SEQ ID NO.1 to SEQ ID NO.8, or the sequence is optimized or modified. Compared with the traditional antibody, the aptamer disclosed by the invention has the advantages of wide identification target range, strong specificity, strong affinity, low toxicity and immunogenicity, low cost and time saving in-vitro synthesis, can be loaded or modified by the aptamer, enhances the functionality of the aptamer and achieves the expected treatment target. The short-chain aptamer provided by the invention is used and is modified and labeled, so that the epithelial cells and tissues of ovarian cancer can be identified and detected, the process is quick and simple, and a new thought is provided for early detection and clinical treatment of ovarian cancer. |
priorityDate | 2020-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.