http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111944034-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111944034-B |
titleOfInvention | Stable polypeptide inhibitor derived from SNAIL1 based on LSD1 substrate and application thereof |
abstract | The invention provides a polypeptide inhibitor, the amino acid sequence structure of which is shown as follows: the invention also provides application of the polypeptide inhibitor in preparing a medicament for inhibiting the enzymatic activity of LSD 1. The polypeptide can be covalently bound with cysteine (Cys360) near an LSD1 enzyme activity pocket, so that the polypeptide plays a role in inhibiting the activity of LSD1 protease and can be used for in-vivo anti-tumor treatment. |
priorityDate | 2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 95.