http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111943884-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a73392b60964c20bd62cd4a444c3dbbf |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-73 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-73 |
filingDate | 2019-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c16fe05a7ce38ad0bfe433f1cb04d519 |
publicationDate | 2020-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111943884-A |
titleOfInvention | A kind of preparation method of pharmaceutical intermediate 2-chloro-3-aminopyridine |
abstract | The invention discloses a preparation method of a pharmaceutical intermediate 2-chloro-3-aminopyridine, comprising the following steps: S1, preparation of nicotinamide; S2, preparation of 3-aminopyridine; S3, crude product of 2-chloro-3-aminopyridine Preparation; S4, refining. The raw materials used in the invention are easy to obtain, low in price, mild in reaction conditions, easy to separate products, have high purity, high yield, less three wastes, less pollution, and are suitable for large-scale production; the invention avoids the use of chlorine, zinc powder and other dangers and The expensive raw materials have industrial application prospects; in the present invention, the organic solvent adopts ethyl acetate, toluene and dichloromethane, and the ethyl acetate, toluene and dichloromethane can be recycled. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111138352-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111138352-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114957030-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114957030-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113461605-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113582919-A |
priorityDate | 2019-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.