http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111936467-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-233 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 |
| filingDate | 2019-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111936467-B |
| titleOfInvention | Crystallization of Compounds as c-Met Kinase Inhibitors, Methods for Their Preparation and Use |
| abstract | The application belongs to the field of medicinal chemistry, and relates to the crystallization of compounds as c-Met kinase inhibitors, in particular to N-(4-((7-((1-(cyclopentylamino)cyclopropanyl)methoxy) Crystallization of -6-methoxyquinolin-4-yl)oxy)-3-fluorophenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide and preparation thereof Methods, crystallographic compositions, pharmaceutical compositions, and use of the crystals to treat diseases associated with inhibition of growth factor receptor protein tyrosine kinase activity. The crystals of the present application have excellent properties in at least one aspect of pharmacokinetics, bioavailability, hygroscopicity, stability, solubility, purity, ease of preparation, and the like. |
| priorityDate | 2018-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.