http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111929370-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-34 |
| filingDate | 2020-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111929370-B |
| titleOfInvention | Method for detecting related substances in pregabalin oral solution |
| abstract | The invention belongs to the field of medicines, and relates to a method for detecting related substances in a pregabalin oral solution. Specifically, the invention relates to a method for detecting related substances in a pregabalin oral solution, which is an HPLC method, wherein HPLC conditions are as follows: the chromatographic column is an octadecylsilane chemically bonded silica gel column; the column temperature is 20-40 ℃; the mobile phase A is 20-30mmol/L potassium dihydrogen phosphate solution, and the pH value is 6.2-7.0; the mobile phase B is methanol; the flow rate is 0.5-1.5 mL/min; the sample amount is 10-30 mu L; the detection wavelength is 210 nm. The method has high sensitivity, good repeatability and high accuracy, can be used for quality control of related substances of the pregabalin oral solution, and is obviously superior to detection methods in United states pharmacopoeia and European pharmacopoeia. |
| priorityDate | 2020-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.