Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24ae3ff27b64d8d6516ec5127c1ac829 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 |
filingDate |
2020-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ae16c6a4c00bb6a61eece3fb412bccb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c0cc8aea58c61a9faad9ae6f47f9b3f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11b866cc5a64341a585c153758ea7802 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f95ce066631f78c26b90c50cd979522 |
publicationDate |
2020-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-111926069-A |
titleOfInvention |
Application of miR-204-5p in irritable bowel syndrome |
abstract |
The invention provides the application of miR-204-5p in irritable bowel syndrome, and belongs to the technical fields of crude drug medicine and molecular biology. The present invention proves for the first time that in irritable bowel syndrome patients and mouse disease models, the expression level of miR-204-5p is significantly lower than that in the normal control group, which is important for guiding the treatment of irritable bowel syndrome visceral hypersensitivity reference meaning. Further research confirmed that miR-204-5p plays a protective role in the occurrence of visceral hypersensitivity in irritable bowel syndrome. Specifically, miR-204-5p may participate in the regulation of visceral sensitivity by changing the expression of EphB2 protein, and the present invention is effective It enriches the treatment plan of visceral hypersensitivity of irritable bowel syndrome, so it has good practical application value. |
priorityDate |
2020-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |