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filingDate 2020-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ae16c6a4c00bb6a61eece3fb412bccb
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publicationDate 2020-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111926069-A
titleOfInvention Application of miR-204-5p in irritable bowel syndrome
abstract The invention provides the application of miR-204-5p in irritable bowel syndrome, and belongs to the technical fields of crude drug medicine and molecular biology. The present invention proves for the first time that in irritable bowel syndrome patients and mouse disease models, the expression level of miR-204-5p is significantly lower than that in the normal control group, which is important for guiding the treatment of irritable bowel syndrome visceral hypersensitivity reference meaning. Further research confirmed that miR-204-5p plays a protective role in the occurrence of visceral hypersensitivity in irritable bowel syndrome. Specifically, miR-204-5p may participate in the regulation of visceral sensitivity by changing the expression of EphB2 protein, and the present invention is effective It enriches the treatment plan of visceral hypersensitivity of irritable bowel syndrome, so it has good practical application value.
priorityDate 2020-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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