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filingDate 2020-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ac1e699b5bcb40fdb8cea93d53f63b2
publicationDate 2020-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111920702-A
titleOfInvention Retinol nanoliposome and preparation method thereof
abstract A retinol nanoliposome and a preparation method thereof, relate to the technical field of cosmetic preparation, have no residual toxic organic solvent, are environmentally friendly, the prepared nanoliposome has a uniform particle size distribution, high encapsulation efficiency and is stable Good performance and continuous production. The method for preparing retinol nanoliposomes of the present invention includes the following steps: mixing and dissolving retinol, film material, stabilizer, antioxidant and organic solvent, forming a film while removing the organic solvent; adding The ionized water is hydrated to obtain a crude suspension of retinol liposomes; the crude suspension is subjected to high pressure homogenization treatment, and subjected to an extruder to obtain the retinol nanoliposomes. The retinol nanoliposome and its preparation method are mainly used in anti-wrinkle, anti-aging, anti-photoaging water, essence, lotion cream and other products.
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