http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111909200-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5022 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-50 |
| filingDate | 2020-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111909200-B |
| titleOfInvention | Preparation method of tri (4-carboxybiphenyl) phosphine with high reproducibility |
| abstract | The invention relates to the technical field of organic methodology, in particular to a preparation method of high-reproducibility tri (4-carboxybiphenyl) phosphine, which comprises the steps of reacting a hydroxyl-substituted phosphorus precursor with p-toluenesulfonyl chloride, carrying out Suzuki coupling reaction on the formed compound to obtain a methyl ester compound of a pentavalent phosphorus ligand, and reducing and hydrolyzing through chlorosilane to obtain the high-purity tri (4-carboxybiphenyl) phosphine. The synthesis method of tris (4-carboxybiphenyl) phosphine has high reproducibility, and avoids the use of high-risk organic reagents such as butyl lithium and the like to synthesize brominated precursors. The synthesis method of tris (4-carboxybiphenyl) phosphine has high yield and is suitable for large-scale production. |
| priorityDate | 2020-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.