http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111888463-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2503-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2503-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0356 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2292 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-165 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
filingDate | 2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111888463-B |
titleOfInvention | Thymosin beta 4 medicinal preparation for treating depression, preparation method and application thereof |
abstract | The invention discloses a thymosin beta 4 medicinal preparation for treating depression, a preparation method and application thereof, and belongs to the technical field of disease treatment. The invention mainly induces the mouse depression-like behavior by establishing a chronic social contusion stress model (CSDS), and the model has the advantages that the model simulates the social attributes in human chronic stress, and after the model is nasally administered with T beta 4 for 7 consecutive days, the depression level is evaluated by the behavioral tests such as Social Interaction Test (SIT), Tail Suspension Test (TST), sugar water preference test (SPT) and the like, and the result shows that the T beta 4 has the rapid antidepressant effect in the mouse and can reverse the CSDS-induced depression-like behavior within 7 days. |
priorityDate | 2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.