| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2fa4878428920816401de784cae67f2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B30-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 |
| filingDate |
2020-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_345be0cd4925d9d74cacca9b345a4b46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dde332cfb638974d22b640dacfc6cf96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc2fb6105bce45a7d689199edd614b28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b649591f91e11ba146e1b95212da30d0 |
| publicationDate |
2020-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-111883203-A |
| titleOfInvention |
Construction method of model for predicting PD-1 curative effect |
| abstract |
The invention discloses a method for constructing a model for predicting the curative effect of PD-1, which comprises the following steps: 1) selecting RNA-seq of a sample of a punctured or paraffin tissue within one month before the administration time as a baseline during which the patient is not receiving other treatment; 2) CT scans were performed every 3 months after PD-1/PD-L1 treatment. 3) Samples were subjected to routine RNA-seq sequencing. 4) RNA-seq bioinformatics analysis. 5) And (3) constructing and screening RNA-seq data characteristics for predicting the curative effect of PD-1. 6) And (3) constructing a model for predicting the curative effect of the PD-1. Compared with the existing PD-1 curative effect prediction molecular marker and RNA sequencing molecular marker, the invention has more accurate prediction result and lower cost. |
| priorityDate |
2020-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |