http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111875700-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-165 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54313 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56983 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-10 |
filingDate | 2020-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111875700-B |
titleOfInvention | Single-chain antibody of anti SARS-COV-2 virus N protein and its use |
abstract | The invention provides a single-chain antibody for resisting SARS-COV-2 virus N protein, the single-chain antibody can identify SARS-COV-2 virus N protein, the single-chain antibody includes heavy chain variable region and light chain variable region: the heavy chain variable region has the sequence shown in SEQ ID NO: 1-SEQ ID NO: 3, and three complementarity determining regions of the amino acid sequence set forth in seq id no; the light chain variable region has the sequence shown in SEQ ID NO: 4-SEQ ID NO: 6, and (b) three complementarity determining regions of the amino acid sequence set forth in figure 6. The EC50 of the single-chain antibody bound to the N protein is 1.339 ng/ml. The antibody can be used for quality control antibodies of a new crown antibody detection kit, the specificity of the antibody detected by a colloidal gold kit is good, and the concentration of the detected antibody is as low as 125 ng/ml. |
priorityDate | 2020-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 434.