| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44cba720f147154e02b7d2ee8b06154a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-236
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-608
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-42 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-0076
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-0035
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-0029 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L33-00 |
| filingDate |
2019-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6afb0020dc62f4580d21f5b6f2601d10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2b7e2a789abfd7e84c149da4cafc530
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c141443ef0ef13d1d9adcf364d7f075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7739bb381530c3a17e8b7fc204cbfec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1edf32f7462889860982a087da4d1d1d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_233d778ffa55b5c1b7a059b8c10d84b9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aea32f75783b1d42f99484d327f112bc |
| publicationDate |
2020-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-111867647-A |
| titleOfInvention |
Improvements in methods for immobilizing biological substances |
| abstract |
According to the present invention, there is provided in particular a method for producing a solid object having a surface comprising a layered coating of cationic and anionic polymers, wherein the outer coating comprises an anticoagulant substance, the method comprising the steps of: i ) treating the surface of the solid object with a cationic polymer; ii) treating the surface with an anionic polymer; iii) optionally repeating steps i) and ii) one or more times; iv) treating the surface with a cationic polymer; and v) treating the outermost layer of the cationic polymer with an anticoagulant substance, thereby covalently linking the anticoagulant substance to the outermost layer of the cationic polymer; wherein the anionic polymer is characterized as having: (a) 650kDa-10,000kDa and (b) a solution charge density of >4 μeq/g; and wherein step ii) is performed at a salt concentration of 0.25M-5.0M. |
| priorityDate |
2018-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |