http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111855828-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-324 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-74 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-74 |
filingDate | 2020-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111855828-B |
titleOfInvention | Method for simultaneously determining content of pregabalin and hydroxyphenyl bacteriostatic agent |
abstract | The invention belongs to the field of medicines, and relates to a method for determining the content of pregabalin and hydroxyphenyl bacteriostatic agents. Specifically, the invention relates to a method for simultaneously determining pregabalin content and hydroxyphenyl bacteriostatic agent content in a pregabalin oral solution, which is an HPLC method, wherein the HPLC conditions are as follows: the chromatographic column is an octadecylsilane chemically bonded silica gel column; the column temperature is 20-40 ℃; the mobile phase A is 20-30mmol/L potassium dihydrogen phosphate solution, and the pH value is 6.2-7.0; the mobile phase B is methanol; the flow rate is 0.5-1.5 mL/min; the sample amount is 10-30 mu L; the detection wavelength is 210 nm. The method has the advantages of good specificity, high sensitivity, good repeatability and high accuracy, and can be used for quality control of the pregabalin oral solution. |
priorityDate | 2020-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.